[Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura].

The association of pregnancy with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.

Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome occurs more commonly in women and among women is commonly associated with pregnancy. Case series of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome from 1964 to 2002 were reviewed (1) to document the reports of occurrence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome during pregnancy and (2) to search...

Is there a shared pathophysiology for thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome?

Thrombotic microangiopathy is characterized by microvascular thrombosis coupled with thrombocytopenia, hemolytic anemia, and red blood cell fragmentation. Familiar to nephrologists and hematologists alike, classically associated with thrombotic microangiopathy are the hemolytic-uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP), the histories and presentations of which are clos...

A case of atypical hemolytic uremic syndrome associated with the c.1273C>T mutation in the complement C3 gene

Thromb Haemost 2005;3:1432-6. 4. Dashe JS, Ramin SM, Cunningham FG. The long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy. Obstet Gynecol 1998;91:662-8. 5. Miner PE, Nutt RL, Thomas ME. Thrombotic thrombocytopenic purpura occurring in pregnancy. Am J Obstet Gynecol 1955;70:611-7. 6. Weiner CP. Thrombotic microan...

Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome: much progress and many remaining issues.

Hemolytic-Uremic Syndrome

Hemolytic-uremic syndrome (HUS) is the most common cause of acute renal failure in children and is increasingly recognized in adults.[1, 2] Thrombotic thrombocytopenic purpura (TTP), childhood HUS, and adult HUS differ in their clinical presentations, but these conditions have many common features. Gasser et al first described hemolytic-uremic syndrome (HUS) in 1955. In 1988, Wardle described h...